Search results
Results From The WOW.Com Content Network
Serious side effects may include low blood pressure or heart attack. [10] Whether use is safe during pregnancy or breastfeeding is unclear. [2] [10] When used by people with liver problems, and in elderly individuals, doses should be reduced. [10] Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10]
Lisinopril/amlodipine, sold under the brand name Lisonorm among others, is a medication used to treat high blood pressure. [ 1] It is a combination of lisinopril an ACE inhibitor with amlodipine a calcium channel blocker. [ 1] It may be used when blood pressure is not well controlled with each of the two agents alone. [ 4]
Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure. [ 1] It is a combination of amlodipine, as the besilate, a calcium channel blocker, and benazepril, an angiotensin converting enzyme inhibitor. [ 1] It may be used if a single agent is not sufficient. [ 1]
In Wikidata. Calcium channel blockers ( CCB ), calcium channel antagonists or calcium antagonists[ 2] are a group of medications that disrupt the movement of calcium ( Ca2+. ) through calcium channels. [ 3] Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension.
The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive.
The use of racemic amlodipine is commonly associated with adverse events like peripheral edema and other side effects like headache, dizziness, flushing and abdominal pain. [13] Controlled clinical trials showed that levamlodipine is rarely associated with these side effects. [ 14 ]
Lisinopril is an ACE inhibitor, meaning it blocks the actions of angiotensin-converting enzyme (ACE) in the renin–angiotensin–aldosterone system (RAAS), preventing angiotensin I from being converted to angiotensin II. Angiotensin II is a potent direct vasoconstrictor and a stimulator of aldosterone release.
Alpha blockers work by blocking the effect of nerves in the sympathetic nervous system. This is done by binding to the alpha receptors in smooth muscle or blood vessels. [ 37] α-blockers can bind both reversibly and irreversibly. [ 2] There are several α receptors throughout the body where these drugs can bind.