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  2. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by the American ...

  3. Depression (mood) - Wikipedia

    en.wikipedia.org/wiki/Depression_(mood)

    Depression is a mental state of low mood and aversion to activity. [3] It affects more than 280 million people of all ages (about 3.5% of the global population). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5] Depressed people often experience loss of motivation or interest in, or reduced pleasure or ...

  4. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The study of reward in depression is limited by heterogeneity in the definition and conceptualizations of reward and anhedonia. Anhedonia is broadly defined as a reduced ability to feel pleasure , but questionnaires and clinical assessments rarely distinguish between motivational "wanting" and consummatory "liking".

  5. Mood disorder - Wikipedia

    en.wikipedia.org/wiki/Mood_disorder

    Antidepressants, mood stabilizers, antipsychotics [1] A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder [2] where a disturbance in the person's mood is the main underlying feature. [3] The classification is in the Diagnostic and Statistical Manual of Mental Disorders (DSM ...

  6. Major depressive episode - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_episode

    Medication. Antidepressants. A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety ...

  7. History of depression - Wikipedia

    en.wikipedia.org/wiki/History_of_depression

    What was previously known as melancholia and is now known as clinical depression, major depression, or simply depression and commonly referred to as major depressive disorder by many health care professionals, has a long history, with similar conditions being described at least as far back as classical times.

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