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Graves' ophthalmopathy, also known as thyroid eye disease ( TED ), is an autoimmune inflammatory disorder of the orbit and periorbital tissues, characterized by upper eyelid retraction, lid lag, swelling, redness ( erythema ), conjunctivitis, and bulging eyes ( exophthalmos ). [ 1] It occurs most commonly in individuals with Graves' disease ...
Teprotumumab. Teprotumumab, sold under the brand name Tepezza, is a medication used to treat adults with thyroid eye disease, a rare condition where the muscles and fatty tissues behind the eye become inflamed, causing the eyes to bulge outwards. [ 2][ 3] The most common side effects are muscle spasm, nausea, hair loss, diarrhea, fatigue, high ...
Graves disease, also known as toxic diffuse goiter or Basedow’s disease, is an autoimmune disease that affects the thyroid. [ 1] It frequently results in and is the most common cause of hyperthyroidism. [ 5] It also often results in an enlarged thyroid. [ 1] Signs and symptoms of hyperthyroidism may include irritability, muscle weakness ...
Shares of the company rose 4.2% in extended trading after the drug regulator said Tepezza is the first approved treatment for the vision-threatening autoimmune disorder, in which the muscles and ...
In the absence of Graves' ophthalmopathy, patients may demonstrate other ophthalmic symptoms and signs due to hyperthyroidism: Dry eyes (due to loss of corneal moisture). [ 24] A sense of irritation, discomfort, or pain in the eyes. A tingling sensation behind the eyes or the feeling of grit or sand in the eyes.
Another 30 years would pass before she was diagnosed with thyroid eye disease (TED), which is related to Graves’ but requires a separate treatment, the CNN report noted. “I’m a sprinter.
Toxic multinodular goiter is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world, whereas iodine deficiency is the most common cause of hypothyroidism in developing-world countries where the population is iodine-deficient. (Decreased iodine leads to decreased thyroid hormone.)
Thyrotoxic myopathy ( TM) is a neuromuscular disorder that develops due to the overproduction of the thyroid hormone thyroxine. Also known as hyperthyroid myopathy, TM is one of many myopathies that lead to muscle weakness and muscle tissue breakdown. Evidence indicates the onset may be caused by hyperthyroidism. [ 1]
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