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685,000 (global, 2020) [ 6] Breast cancer is a cancer that develops from breast tissue. [ 7] Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. [ 1] In those with distant spread of the ...
The American Cancer Society reports 5-year relative survival rates of over 70% for women with stage 0-III breast cancer with a 5-year relative survival rate close to 100% for women with stage 0 or stage I breast cancer. The 5-year relative survival rate drops to 22% for women with stage IV ( metastatic) breast cancer. [3]
Metastatic breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; [ 1] there is ...
James Paget. Paget's disease of the breast (also known as mammary Paget's disease) is a rare skin change at the nipple nearly always associated with underlying breast cancer. [ 2] Paget's disease of the breast was first described by Sir James Paget in 1874. [ 3] The condition is an uncommon disease accounting for 1 to 4% of all breast cancers ...
Uterine serous carcinoma is a malignant form of serous tumor that originates in the uterus. It is an uncommon form of endometrial cancer that typically arises in postmenopausal women. It is typically diagnosed on endometrial biopsy, prompted by post-menopausal bleeding . Unlike the more common low-grade endometrioid endometrial adenocarcinoma ...
The 2012 World Health Organization (WHO) classification of tumors of the breast [ 11] which includes benign (generally harmless) tumors and malignant (cancerous) tumors, recommends the following pathological types: Invasive breast carcinomas. Invasive carcinoma. Most are "not otherwise specified".
The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer. [1] [2] Its value is calculated using three pathological criteria: the size of the tumour; the number of involved lymph nodes; and the grade of the tumour. [1] It is calculated to select patients for adjuvant treatment.
In developed countries, about 99% of breast cancer cases are diagnosed in female patients; in a few African countries, which represent the highest incidence of male breast cancer, males account for 5–15% of cases. The rate of male breast cancer appears to be rising somewhat. Male breast cancer patients tend to be older than female ones.
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