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1.8 million (2020) [ 3] Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
For patients with tumor PD-L1 expression level of 1–49%, monotherapy with pembrolizumab as per KEYNOTE-042 is an appealing option, especially for smoker males. Treatment of patients with metastatic non-small cell lung cancer (NSCLC). First line Immunotherapy for Non-Small Cell Lung Cancer. Keynote-024
A Pancoast tumor is a tumor of the apex of the lung. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung. It typically spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non-small-cell lung cancers . The growing tumor can cause compression of many ...
Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, accounting for 80-85% of all cases. It develops when abnormal lung cells grow uncontrollably, forming a tumor. There are ...
Adenocarcinoma of the lung. A gross pathological specimen of a pulmonary adenocarcinoma, removed in a lobectomy. Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. [ 1] It is classified as one of several non-small cell lung ...
Lung cancer staging is the assessment of the extent to which a lung cancer has spread from its original source. As with most cancers, staging is an important determinant of treatment and prognosis. In general, more advanced stages of cancer are less amenable to treatment and have a worse prognosis. The initial evaluation of non-small cell lung ...
Oncology. Giant-cell carcinoma of the lung ( GCCL) is a rare histological form of large-cell lung carcinoma, a subtype of undifferentiated lung cancer, traditionally classified within the non-small-cell lung carcinomas (NSCLC). The characteristic feature of this highly lethal malignancy is the distinctive light microscopic appearance of its ...
Oncology . Adenocarcinoma in situ(AIS) of the lung—previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma. It tends to arise in the distalbronchiolesor alveoliand is defined by a non-invasive growth pattern. This small solitary tumor exhibits pure alveolar distribution (lepidic growth ...
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