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Metandienone was formerly approved and marketed as a form of androgen replacement therapy for the treatment of hypogonadism in men, but has since been discontinued and withdrawn in most countries, including in the United States. [ 15][ 4][ 6] It was given at a dosage of 5 to 10 mg/day in men and 2.5 mg/day in women. [ 16][ 17][ 1] v. t.
Testicular cancer. 7.4 × 5.5-cm seminoma in a radical orchiectomy specimen. Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. [ 2] Symptoms may include a lump in the testicle or swelling or pain in the scrotum. [ 2] Treatment may result in infertility.
Testicular atrophy is a medical condition in which one or both testicles (or "testes") diminish in size and may be accompanied by reduced testicular function. Testicular atrophy is not related to the temporary shrinkage of the surrounding scrotum, which might occur in response to cold temperature. As the testicles are involved in testosterone ...
Late-onset hypogonadism. Late-onset hypogonadism ( LOH) or testosterone deficiency syndrome ( TDS) [ 1][ 2] is a term for a condition in older men characterized by measurably low testosterone levels and clinical symptoms mostly of a sexual nature, including decreased desire for mating, fewer spontaneous erections, and erectile dysfunction. [ 3]
Legal status. In Wikidata. Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen ...
Selective androgen receptor modulators ( SARMs) are a class of drugs that selectively activate the androgen receptor in specific tissues, promoting muscle and bone growth while having less effect on male reproductive tissues like the prostate gland . Non-selective steroidal drugs, called anabolic androgenic steroids (AAS), have been used for ...
Hypogonadism means diminished functional activity of the gonads —the testicles or the ovaries —that may result in diminished production of sex hormones. Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism. These are responsible for the observed signs and symptoms ...
Oxandrolone is an androgen and synthetic anabolic steroid (AAS) medication to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications.