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Metandienone was formerly approved and marketed as a form of androgen replacement therapy for the treatment of hypogonadism in men, but has since been discontinued and withdrawn in most countries, including in the United States. [ 15][ 4][ 6] It was given at a dosage of 5 to 10 mg/day in men and 2.5 mg/day in women. [ 16][ 17][ 1] v. t.
Late-onset hypogonadism. Late-onset hypogonadism ( LOH) or testosterone deficiency syndrome ( TDS) [ 1][ 2] is a term for a condition in older men characterized by measurably low testosterone levels and clinical symptoms mostly of a sexual nature, including decreased desire for mating, fewer spontaneous erections, and erectile dysfunction. [ 3]
Testicular atrophy is a medical condition in which one or both testicles (or "testes") diminish in size and may be accompanied by reduced testicular function. Testicular atrophy is not related to the temporary shrinkage of the surrounding scrotum, which might occur in response to cold temperature. As the testicles are involved in testosterone ...
The psychological stress model consists of stressful experiences that a patient with testicular cancer may go through after diagnosis, that caregivers may want to look out for. [30] The stressful experiences consist of 4 main categories: Late side-effects; Fear of tumor relapse; Fertility problems; Social and workplace issues [30]
Although anabolic steroid was originally intended to specifically describe testosterone-derived steroids with a marked dissociation of anabolic and androgenic effect, it is applied today indiscriminately to all steroids with AR agonism-based anabolic effects regardless of their androgenic potency, including even non-synthetic and non ...
Hypogonadism means diminished functional activity of the gonads —the testicles or the ovaries —that may result in diminished production of sex hormones. Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism. These are responsible for the observed signs and symptoms ...
Androgen deprivation therapy ( ADT ), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer. Prostate cancer cells usually require androgen hormones, such as testosterone, to grow. ADT reduces the levels of androgen hormones, with drugs or surgery, to ...
Selective androgen receptor modulators ( SARMs) are a class of drugs that selectively activate the androgen receptor in specific tissues, promoting muscle and bone growth while having less effect on male reproductive tissues like the prostate gland . Non-selective steroidal drugs, called anabolic androgenic steroids (AAS), have been used for ...