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  2. Lipinski's rule of five - Wikipedia

    en.wikipedia.org/wiki/Lipinski's_Rule_of_Five

    Lipinski's rule of five. Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five ( RO5 ), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active ...

  3. National Fraternal Order of Police - Wikipedia

    en.wikipedia.org/wiki/National_Fraternal_Order...

    fop .net. The National Fraternal Order of Police ( FOP) is a fraternal organization consisting of sworn law enforcement officers in the United States. It reports a membership of over 355,000 members organized in 2,100 local chapters (lodges), state lodges, and the national Grand Lodge. The organization attempts to improve the working conditions ...

  4. Walker motifs - Wikipedia

    en.wikipedia.org/wiki/Walker_motifs

    The P-loop main chain is shown in red, the Mg 2+ ion as green sphere and the side chains of the amino acids K16 and S17 are shown as sticks. Walker A motif, also known as the Walker loop, or P-loop, or phosphate-binding loop, is a motif in proteins that is associated with phosphate binding. The motif has the pattern G-x (4)-GK- [TS], where G, K ...

  5. Least objectionable program - Wikipedia

    en.wikipedia.org/wiki/Least_objectionable_program

    Least offensive programming [5] (sometimes abbreviated as LOP) was a strategy employed mainly by major US television networks, approximately from the 1940s to late 1970s, where viewer numbers were thought to be sustained by television programming that offended the fewest viewers. [6] The result was an often mass-produced, bland output of ...

  6. LoopNet - Wikipedia

    en.wikipedia.org/wiki/LoopNet

    LoopNet was founded in 1995 by Dennis DeAndre. Working alongside engineer Steve Midgley, the two built LoopNet into the internet's largest commercial real estate listing service. LoopNet underwent three rounds of private venture capital financing in 1997 (Indo Suez), 1998 (Trinity Capital & Partners) [1] and $20 million in 1999 from fourT5 real ...

  7. Yakuza - Wikipedia

    en.wikipedia.org/wiki/Yakuza

    The yakuza are aging because young people do not readily join, and their average age at the end of 2022 was 54.2 years: 5.4% in their 20s, 12.9% in their 30s, 26.3% in their 40s, 30.8% in their 50s, 12.5% in their 60s, and 11.6% in their 70s or older, with more than half of the members in their 50s or older.

  8. Dunlop (brands) - Wikipedia

    en.wikipedia.org/wiki/Dunlop_(brands)

    Dunlop is a brand of tyre originally produced by the Dunlop Pneumatic Tyre Company from the end of the 19th century, taking its name from John Boyd Dunlop. The brand is used for many other products made from rubber or with rubber components and some with a looser connection to rubber. Ownership of the brand has become fragmented over the years.

  9. Microsoft Loop - Wikipedia

    en.wikipedia.org/wiki/Microsoft_Loop

    Microsoft Loop is an online collaborative workspace that offers a variety of features to help users gather, organize, and build notes, ideas, and projects. It comes with templates for meetings, project planning, and personal tasks, and offers integration with other Microsoft and third-party tools and services. [1]