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Off-label use. Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. [1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.
The success of a multi-center trial for treating children with SCID (severe combined immune deficiency or "bubble boy" disease) from 2000 and 2002, was questioned when two of the ten children treated at the trial's Paris center developed a leukemia-like condition. Clinical trials were halted temporarily in 2002, but resumed after regulatory ...
The Pfizer–BioNTech vaccine must be kept at extremely low temperatures to ensure effectiveness, roughly between −80 and −60 °C (−112 and −76 °F). The vaccine can be stored at 2 to 8 °C (36 to 46 °F) for thirty days before use and at 25 °C (77 °F) or 30 °C (86 °F) for up to two hours before use. During distribution the vaccine ...
The Children's Place in Manhattan (now closed) The company was founded in 1969. It was acquired by Federated Department Stores in 1981. After Campeau Corporation acquired Federated, they sold The Children's Place to a group led by Joseph Sitt in 1988. They became publicly traded on the NASDAQ exchange in 1997 under the ticker symbol PLCE.
Shingles. Shingles, also known as herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [6] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1] Two to four days before the rash occurs there may be tingling or local pain in the area.
The Nordstrom Anniversary Sale is in full swing and if you haven't shopped yet, there's still time. We combed through more than 5,000 items to find you the best deals under $50 — we're talking ...
For the chemical, see Sodium thiosulfate. Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. [3] [4] [5] For cyanide poisoning, it is often used after the medication sodium nitrite and is typically only recommended for ...
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.
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