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Endocrine oncology. Neuroendocrine tumors ( NETs) are neoplasms that arise from cells of the endocrine ( hormonal) and nervous systems. They most commonly occur in the intestine, where they are often called carcinoid tumors, but they are also found in the pancreas, lung, and the rest of the body.
Neuroendocrine differentiation. Neuroendocrine differentiation is a term primarily used in relation to prostate cancers that display a significant neuroendocrine cell population on histopathological examination. These types of prostate cancer comprise true neuroendocrine cancers, such as small cell carcinoma, carcinoid and carcinoid-like tumors ...
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels. Those with high levels of PSA in their blood are at increased ...
A histopathologic diagnosis of prostate cancer is the discernment of whether there is a cancer in the prostate, as well as specifying any subdiagnosis of prostate cancer if possible. The histopathologic subdiagnosis of prostate cancer has implications for the possibility and methodology of any subsequent Gleason scoring. [ 1]
Small-cell carcinoma is a type of highly malignant cancer that most commonly arises within the lung, [ 1] although it can occasionally arise in other body sites, such as the cervix, [ 2] prostate, [ 3] and gastrointestinal tract. Compared to non-small cell carcinoma, small cell carcinoma is more aggressive, with a shorter doubling time, higher ...
Amina Zoubeidi is a Canadian research scientist and prostate cancer researcher. She's a scientist at the Vancouver Coastal Health Research Institute and an associate professor in the Department of Urologic Sciences at the University of British Columbia. During her tenure at UBC, Zoubeidi and her research team developed the first drug that ...
Treatment for prostate cancer may involve active surveillance, surgery, radiation therapy – including brachytherapy ( prostate brachytherapy) and external-beam radiation therapy, proton therapy, high-intensity focused ultrasound (HIFU), cryosurgery, hormonal therapy, chemotherapy, or some combination. Treatments also extend to survivorship ...
Gamma-enolase, also known as enolase 2 (ENO2) or neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene. [ 5][ 6] Gamma-enolase is a phosphopyruvate hydratase . Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin.