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Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; [8] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. [9] [10] Fentanyl is also used as a sedative. [11]
Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug. It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy .
Lean is a proof assistant and a functional programming language. [1] It is based on the calculus of constructions with inductive types. It is an open-source project hosted on GitHub. It was developed primarily by Leonardo de Moura while employed by Microsoft Research and now Amazon Web Services, and has had significant contributions from other ...
Druglikeness. Druglikeness is a qualitative concept used in drug design for how "druglike" a substance is with respect to factors like bioavailability. It is estimated from the molecular structure before the substance is even synthesized and tested. A druglike molecule has properties such as:
Kevin Costner continues to double down on his exit from “Yellowstone,” in which he played lead character John Dutton for four and a half seasons. In a cover story for People magazine, the ...
α-Methylfentanyl was discovered by a team at Janssen Pharmaceutica in the 1960s. [1] In 1976, it began to appear mixed with heroin, as an additive, and the mixture was sometimes also called "China White". It was first identified in the bodies of two drug overdose victims in Orange County, California, in December 1979, who appeared to have died ...
Jenkem is an inhalant and hallucinogen created from fermented human waste.In the mid-1990s, it was reported to be a popular street drug among Zambian youth, created by placing feces and urine in a bottle or a bucket, sealing it with a balloon or lid respectively and leaving it to ferment in the sun; afterwards they would inhale the gases generated.
Israeli forces killed four Palestinians in the occupied West Bank on Monday, Palestinian officials said, and Israel's border police said they had opened fire at a vehicle that tried to run them ...