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Cancer in adolescents and young adults is cancer which occurs in those between the ages of 15 and 39. [1] This occurs in about 70,000 people a year in the United States—accounting for about 5 percent of cancers. This is about six times the number of cancers diagnosed in children ages 0–14. [1]
Cancer cell. Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body for growth and repair. A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells that have died ...
Werner syndrome (WS) or Werner's syndrome, also known as "adult progeria ", [ 1] is a rare, autosomal recessive disorder [ 2] which is characterized by the appearance of premature aging. [ 3] Werner syndrome is named after the German scientist Otto Werner. [ 4] He identified the syndrome in four siblings observed with premature aging, which he ...
111,000 (2015) [ 10] Acute lymphoblastic leukemia ( ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [ 1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [ 1]
The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities. The idea was coined by Douglas Hanahan and Robert Weinberg in their paper " The Hallmarks of Cancer " published January 2000 in Cell.
The cancer stem cell model, also known as the Hierarchical Model proposes that tumors are hierarchically organized (CSCs lying at the apex [6] (Fig. 3).) Within the cancer population of the tumors there are cancer stem cells (CSC) that are tumorigenic cells and are biologically distinct from other subpopulations [7] They have two defining features: their long-term ability to self-renew and ...
101,100 (2015) [ 9] Multiple myeloma ( MM ), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [ 6] Often, no symptoms are noticed initially. [ 10] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [ 10]
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a ...