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It is the most common malignant cancer in children, but the cure rates are also higher for them. Causes: Inherited and environmental factors: Risk factors: Smoking, family history, ionizing radiation, some chemicals such as trichloroethylene, prior chemotherapy, Down syndrome. Diagnostic method: Blood tests, bone marrow biopsy: Treatment
1 million (2015)[4] Deaths. 147,100 (2015)[5] Acute myeloid leukemia(AML) is a cancerof the myeloidline of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrowand bloodand interfere with normal blood cell production.[1]
Deaths. 60,700 (2015) [7] Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [2] [8] Early on, there are typically no symptoms. [2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur.
Multiple myeloma ( MM ), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [6] Often, no symptoms are noticed initially. [10] As it progresses, bone pain, anemia, renal insuficiency, and infections may occur. [10]
Micrograph of a plasmacytoma, a hematological malignancy. Tumors of the hematopoietic and lymphoid tissues ( American English) or tumours of the haematopoietic and lymphoid tissues ( British English) are tumors that affect the blood, bone marrow, lymph, and lymphatic system. [1] [2] Because these tissues are all intimately connected through ...
Plasma cell leukemia ( PCL) is a plasma cell dyscrasia, i.e. a disease involving the malignant degeneration of a subtype of white blood cells called plasma cells. It is the terminal stage and most aggressive form of these dyscrasias, constituting 2% to 4% of all cases of plasma cell malignancies. PCL may present as primary plasma cell leukemia ...
Constitutional Symptoms. Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers. Unexplained night sweats or fever: These may be signs of an immune system cancer. Fever in children rarely points to malignancy, but may merit evaluation.
In oncology, polycythemia vera ( PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [2] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
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