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Prostate-specific antigen (PSA) levels by age remain the same across most populations. A PSA level above 4.0 ng/mL in any age group must be investigated . However, PSA levels can spike in noncancerous conditions, such as benign prostate hypertrophy ( BPH ), urinary tract infections , prostatitis , consumption of testosterone supplements ...
Generally speaking, though, PSA levels for men who are: Age 60 or older: should be at or below 4.0 mg/mL; Age 59 or younger: should be at or below 2.5 mg/mL; The average PSA for men in the younger group is <1.0 mg/mL. Why are my PSA levels elevated? Your PSA levels could be elevated for many reasons.
Doctors will consider your age and the size of your prostate when determining what your PSA score means. In general: For men in their 40s and 50s: A PSA score greater than 2.5 ng/ml is considered abnormal. The median PSA for this age range is 0.6 to 0.7 ng/ml.
Review the typical prostate-specific antigen (PSA) ranges by age and what your next steps might be if yours is higher.
This chart shows how PSA levels change with age, and how various risk factors can inform your decision-making process when discussing prostate cancer testing with your doctor.
The PSA test can detect high levels of PSA that may indicate the presence of prostate cancer. However, many other conditions, such as an enlarged or inflamed prostate, also can increase PSA levels. Therefore, determining what a high PSA score means can be complicated.
The 4Kscore test takes into account four different prostate-specific biomarkers, namely, total PSA, free PSA, intact PSA, and human kallikrein 2, as well as the patient’s age, prior biopsy history, and DRE status to assess the risk of aggressive prostate cancer in someone with an abnormal screening result.