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Dopaminergic means "related to dopamine " (literally, "working on dopamine"), dopamine being a common neurotransmitter. [1] Dopaminergic substances or actions increase dopamine-related activity in the brain. Dopaminergic brain pathways facilitate dopamine-related activity. For example, certain proteins such as the dopamine transporter (DAT ...
Dopaminergic pathways ( dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control. [1] Each pathway is a set of projection neurons, consisting of individual dopaminergic neurons.
The dopaminergic cell groups and pathways make up the dopamine system which is neuromodulatory. Dopaminergic neurons (dopamine-producing nerve cells) are comparatively few in number—a total of around 400,000 in the human brain [40] —and their cell bodies are confined in groups to a few relatively small brain areas. [41]
This is a list of dopaminergic drugs. These are pharmaceutical drugs , naturally occurring compounds and other chemicals that influence the function of the neurotransmitter dopamine . Receptor ligands
Dopaminergic cell groups, DA cell groups, or dopaminergic nuclei are collections of neurons in the central nervous system that synthesize the neurotransmitter dopamine. In the 1960s, dopaminergic neurons or dopamine neurons were first identified and named by Annica Dahlström and Kjell Fuxe , who used histochemical fluorescence . [2]
Dopamine. Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions. [ 1] The ...
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist ( DRA ), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [1]
A dopamine agonist is a compound that activates dopamine receptors. There are two families of dopamine receptors, D 1 -like and D 2 -like. They are all G protein-coupled receptors. D 1 - and D 5 -receptors belong to the D 1 -like family and the D 2 -like family includes D 2, D 3 and D 4 receptors. [1]