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  2. Ciclosporin - Wikipedia

    en.wikipedia.org/wiki/Ciclosporin

    Ciclosporin is indicated to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants. [8] [7] It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis, [23] [7] and as eye drops for treating dry eyes caused by ...

  3. Dry eye syndrome - Wikipedia

    en.wikipedia.org/wiki/Dry_eye_syndrome

    Ciclosporin, steroid eye drops [ 2] Frequency. ~20% [ 5] Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes. [ 2] Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes. Symptoms range from mild and occasional to severe and continuous. [ 3]

  4. Netarsudil - Wikipedia

    en.wikipedia.org/wiki/Netarsudil

    Netarsudil. Netarsudil, sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma. [1] [2] [3] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle glaucoma or ocular ...

  5. Inhaled ciclosporin - Wikipedia

    en.wikipedia.org/wiki/Inhaled_ciclosporin

    Inhaled ciclosporin. Ciclosporin is a cyclic polypeptide that has been used widely as an orally-available immunosuppressant. [1] It was originally used to prevent transplant rejection of solid organs but has also found use as an orally administered agent to treat psoriasis, [2] rheumatoid arthritis, [3] dry eye [4] and other auto-immune related ...

  6. Ripasudil - Wikipedia

    en.wikipedia.org/wiki/Ripasudil

    Twice daily in right eye 26 weeks 1.0% No mortality at all doses. After ocular administration, symptoms included hypermia of the bulbar and papebral conjunctiva, white spots in the lens. Dogs Once a day in right eye and orally 13 weeks 2.0% in eye, 7.5 mg/kg/day by mouth No mortality observed. Monkey Once a day in right eye 52 weeks 2.0%

  7. Bromfenac - Wikipedia

    en.wikipedia.org/wiki/Bromfenac

    Bromfenac. Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) [ 2] marketed in the US as an ophthalmic solution (brand names Prolensa and Bromday, [ 3] prior formulation brand name Xibrom, which has since been discontinued) by ISTA Pharmaceuticals for short-term, local use. Prolensa and Bromday are the once-daily formulation of ...

  8. Ophthalmic drug administration - Wikipedia

    en.wikipedia.org/wiki/Ophthalmic_drug_administration

    Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1] However, there are many challenges associated with topical ...

  9. Tetryzoline - Wikipedia

    en.wikipedia.org/wiki/Tetryzoline

    In one study, 10 people were given two drops of 0.5 mg/mL of tetryzoline eye drops (0.025–0.05 mg) at 0 hrs, 4 hrs, 8 hrs, and 12 hrs. Within a 24-hour time window, since the last dose of tetryzoline, the blood serum concentration of tetryzoline in the test subjects was 0.068-0.380 ng/mL and the urine concentration was 13–210 ng/mL. Both ...

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