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2. Hormone receptor positive breast tumor - Wikipedia

   en.wikipedia.org/wiki/Hormone_receptor_positive...

   ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes that have different prognoses and may have different ...

3. Breast cancer classification - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer_classification

   These treatments are now some of the most effective adjuvant treatments of breast cancer. Estrogen receptor positive (ER+) cancer cells depend on estrogen for their growth, so they can be treated with drugs to reduce either the effect of estrogen (e.g. tamoxifen) or the actual level of estrogen (e.g. aromatase inhibitors), and generally have a ...

4. Tamoxifen - Wikipedia

   en.wikipedia.org/wiki/Tamoxifen

   Tamoxifen is used for the treatment of both early and advanced estrogen receptor-positive (ER-positive or ER+) breast cancer in pre-and postmenopausal women. [23] Tamoxifen increases the risk of postmenopausal bleeding, endometrial polyps, hyperplasia, and endometrial cancer; using tamoxifen with an intrauterine system releasing levonorgestrel might increase vaginal bleeding after 1 to 2 years ...

5. Invasive carcinoma of no special type - Wikipedia

   en.wikipedia.org/wiki/Invasive_carcinoma_of_no...

   Invasive carcinoma NST is a type of breast cancer. It is one of the invasive breast cancers that originates from the breast ductal system, so that it is a type of ductal carcinoma. A defining feature of this ductal carcinoma is that it lacks the "specific differentiating features" of other types of ductal carcinomas.

6. Estrogen receptor - Wikipedia

   en.wikipedia.org/wiki/Estrogen_receptor

   Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry. Two hypotheses have been proposed to explain why this causes tumorigenesis , and the available evidence suggests that both mechanisms contribute:

7. Selective estrogen receptor modulator - Wikipedia

   en.wikipedia.org/wiki/Selective_estrogen...

   Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonist/antagonists (ERAAs), [1] [2] is a class of drugs that act on estrogen receptors (ER). [3] A characteristic that distinguishes these substances from pure ER agonists-antagonists (ex., full agonists and silent antagonists) is that their action is different in various tissues, allowing them to selectively ...