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  2. New weight-loss drugs might be a breakthrough, but ... - AOL

    www.aol.com/weight-loss-drugs-might-breakthrough...

    Skeptics of weight-loss injection medications pose concerns about weight regain post-treatment. In a 2022 experiment in the “Diabetes, Obesity and Metabolism journal,” they studied 1,961 ...

  3. Fractyl Health Receives FDA Breakthrough Device Designation ...

    lite.aol.com/tech/story/0022/20240730/9195414.htm

    Fractyl Health Receives FDA Breakthrough Device Designation for Revita in Weight Maintenance for People with Obesity Who Discontinue GLP-1 Based Drugs 07/30/2024 11:00 -0400 Breakthrough Device Designations are granted by the U.S. FDA to expedite review of promising technologies that address high unmet needs and may improve the lives of people ...

  4. Doctors are prescribing the weight loss drug semaglutide ...

    www.aol.com/lifestyle/doctors-prescribing-weight...

    Given that people on other prescription weight-loss medications lose, on average, 3% to 12% of their body weight after a year, it’s not surprising that semaglutide’s results are leading some ...

  5. Breakthrough therapy - Wikipedia

    en.wikipedia.org/wiki/Breakthrough_therapy

    A breakthrough therapy is a drug: • intended alone or in combination with one or more other drugs to treat a serious or life threatening disease or condition and. • preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints, such as ...

  6. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Amgen. non-small cell lung cancer with KRAS G12C mutation. Avapritinib. Blueprint Medicines Corp. granted for two indications: mast cell leukemia and advanced systemic mastocytosis. Belumosudil. Kadmon Pharmaceuticals. chronic graft-versus-host disease. Pembrolizumab.

  7. Orlistat - Wikipedia

    en.wikipedia.org/wiki/Orlistat

    Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. [4]

  8. Bariatric surgery - Wikipedia

    en.wikipedia.org/wiki/Bariatric_surgery

    Bariatric surgery (or metabolic surgery or weight loss surgery) is a medical term for surgical procedures used to manage obesity and obesity-related conditions. [1] [2] Long term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size, reduction of nutrient absorption, or a combination of these.

  9. FDA Grants Breakthrough Therapy Designation to Asfotase Alfa for Perinatal-, Infantile- and Juvenile-Onset Hypophosphatasia (HPP) LAUSANNE, Switzerland--(BUSINESS WIRE)-- Alexion Pharma ...

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