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  2. New weight-loss drugs might be a breakthrough, but ... - AOL

    www.aol.com/weight-loss-drugs-might-breakthrough...

    Skeptics of weight-loss injection medications pose concerns about weight regain post-treatment. In a 2022 experiment in the “Diabetes, Obesity and Metabolism journal,” they studied 1,961 ...

  3. Breakthrough therapy - Wikipedia

    en.wikipedia.org/wiki/Breakthrough_therapy

    A breakthrough therapy designation can be assigned to a drug if "it is a drug which is intended alone or in combination with one or more other drugs to treat a serious or life threatening disease or condition" and if the preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints, such as ...

  4. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Amgen. non-small cell lung cancer with KRAS G12C mutation. Avapritinib. Blueprint Medicines Corp. granted for two indications: mast cell leukemia and advanced systemic mastocytosis. Belumosudil. Kadmon Pharmaceuticals. chronic graft-versus-host disease. Pembrolizumab.

  5. Pfizer moves forward with once-daily weight-loss pill - AOL

    www.aol.com/news/pfizer-moves-forward-once-daily...

    July 11, 2024 at 8:34 AM. By Michael Erman and Manas Mishra. (Reuters) -Pfizer plans to move a reworked, once-a-day version of its weight-loss pill danuglipron into clinical trials later this year ...

  6. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    And there were no adverse effects on weight, blood pressure, heart rate, or liver function. It’s expected to be available in early 2024. Ketamine therapy for depression

  7. Weight loss - Wikipedia

    en.wikipedia.org/wiki/Weight_loss

    Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...

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