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Huntington's disease ( HD ), also known as Huntington's chorea, is an incurable neurodegenerative disease [ 7] that is mostly inherited. [ 8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [ 9][ 1] A general lack of coordination and an unsteady gait often follow. [ 2]
A neurodegenerative diseaseis caused by the progressive loss of neurons, in the process known as neurodegeneration. [2][3]Neuronal damage may also ultimately result in their death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system ...
A demyelinating disease refers to any disease affecting the nervous system where the myelin sheath surrounding neurons is damaged. [ 1] This damage disrupts the transmission of signals through the affected nerves, resulting in a decrease in their conduction ability. Consequently, this reduction in conduction can lead to deficiencies in ...
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure.
Pathophysiology (or physiopathology) is a branch of study, at the intersection of pathology and physiology, concerning disordered physiological processes that cause, result from, or are otherwise associated with a disease or injury. Pathology is the medical discipline that describes conditions typically observed during a disease state, whereas ...
Addison's disease, also known as primary adrenal insufficiency, [ 4] is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands ( adrenal cortex ), causing adrenal insufficiency. [ 5][ 6] Symptoms generally come on ...
Iatrogenesis is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence. [ 1][ 2][ 3] First used in this sense in 1924, [ 1] the term was introduced to sociology in 1976 by Ivan Illich, alleging that industrialized societies impair quality of life ...
Gerstmann–Sträussler–Scheinker syndrome ( GSS) is an extremely rare, always fatal (due to it being caused by prions) neurodegenerative disease that affects patients from 20 to 60 years in age. It is exclusively heritable, and is found in only a few families all over the world. [1] It is, however, classified with the transmissible ...