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Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, and lipid modulator. [ 2 ] A main target of PEA is proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α). [ 3 ][ 4 ] PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119. [ 5 ]
Like loperamide and other opioids, morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. The gastrointestinal effects of morphine are mediated primarily by μ-opioid receptors in the bowel. By inhibiting gastric emptying and reducing propulsive peristalsis of the intestine, morphine ...
Trademarked in 1918, Anacin is one of the oldest brands of pain relievers in the United States. It originally contained acetophenetidin (phenacetin) and was promoted as "aspirin-free relief," but was reformulated in the 1980s following the FDA's ruling to withdraw phenacetin from the market in 1983 due to concerns over its carcinogenic properties.
Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling ...
Sunscreen, also known as sunblock[ a ] , sun lotion or sun cream, is a photoprotective topical product for the skin that helps protect against sunburn and prevent skin cancer. Sunscreens come as lotions, sprays, gels, foams (such as an expanded foam lotion or whipped lotion [ 4 ]), sticks, powders and other topical products.
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