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The first to be discovered was TDP-43 protein, [77] a nuclear protein that aggregates in the cytoplasm of motor neurons in almost all cases of ALS; however, mutations in TARDBP, the gene that codes for TDP-43, are a rare cause of ALS. [10] FUS codes for FUS, another RNA-binding protein with a similar function to TDP-43, which can cause ALS when ...
In economics, time preference (or time discounting, [1] delay discounting, temporal discounting, [2] long-term orientation [3]) is the current relative valuation placed on receiving a good or some cash at an earlier date compared with receiving it at a later date. [1] Time preferences are captured mathematically in the discount function. The ...
In economics and finance, present value (PV), also known as present discounted value, is the value of an expected income stream determined as of the date of valuation.The present value is usually less than the future value because money has interest-earning potential, a characteristic referred to as the time value of money, except during times of negative interest rates, when the present value ...
[46] [47] One of the hotter periods was the Last Interglacial between 115,000 and 130,000 years ago, when sea levels were 6 to 9 metres higher than today. [48] The most recent glacial maximum 20,000 years ago had sea levels that were about 125 metres (410 ft) lower than today. [49]
Generation Z (often shortened to Gen Z), also known as Zoomers, [1] [2] [3] is the demographic cohort succeeding Millennials and preceding Generation Alpha.Researchers and popular media use the mid-to-late 1990s as starting birth years and the early 2010s as ending birth years, with the generation most frequently being defined as people born from 1997 to 2012. [4]
The 2024 United States presidential election will be the 60th quadrennial presidential election, set to be held on Tuesday, November 5, 2024. [1] Voters in each state and the District of Columbia will choose electors to the Electoral College, who will then elect a president and vice president for a term of four years.
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