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Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by the American ...
Depression is a mental state of low mood and aversion to activity. [3] It affects more than 280 million people of all ages (about 3.5% of the global population). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5] Depressed people often experience loss of motivation or interest in, or reduced pleasure or ...
Medication. Antidepressants. A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety ...
A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder [2] where a disturbance in the person's mood is the main underlying feature. [3] The classification is in the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD).
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Physical causes are ruled out with a clinical assessment of depression that measures vitamins, minerals, electrolytes, and hormones. [2] [3] [4] Though psychiatric medication is the most frequently prescribed therapy for major depression, [5] psychotherapy may be effective, either alone or in combination with medication. [6]
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