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Hierarchy of evidence. A hierarchy of evidence, comprising levels of evidence (LOEs), that is, evidence levels (ELs), is a heuristic used to rank the relative strength of results obtained from experimental research, especially medical research. There is broad agreement on the relative strength of large-scale, epidemiological studies.
Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /), sometimes known as the Warburg theory of cancer, postulates that the driver of tumorigenesis is an insufficient cellular respiration caused by insult to mitochondria. [1]
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery ...
The PDF of the paper. " Why Most Published Research Findings Are False " is a 2005 essay written by John Ioannidis, a professor at the Stanford School of Medicine, and published in PLOS Medicine. [1] It is considered foundational to the field of metascience. In the paper, Ioannidis argued that a large number, if not the majority, of published ...
The first Cancer Prevention Study, known as CPS-I, recruited subjects between October 1959 and February 1960. This study included more than 1 million men and women. [1] The participants were followed until 1972. [2] The study showed that the increase in lung cancer mortality rates in women during the study's time period occurred only in smoking ...
Human subject research is systematic, scientific investigation that can be either interventional (a "trial") or observational (no "test article") and involves human beings as research subjects, commonly known as test subjects. Human subject research can be either medical (clinical) research or non-medical (e.g., social science) research. [1]
Hospitals, clinics, clinical research centers. Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an oncologist. [1] The name's etymological origin is the Greek word ὄγκος (ónkos), meaning "tumor", "volume" or "mass". [2]
Experimental cancer treatment. Experimental cancer treatments are mainstream medical therapies intended to treat cancer by improving on, supplementing or replacing conventional methods (surgery, chemotherapy, radiation, and immunotherapy). However, researchers are still trying to determine whether these treatments are safe and effective treatments.