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M1: Cancer has spread to other parts of the body. A cancer’s grade & its stage help doctors and patients understand how serious the disease is and form a treatment plan. Learn about what each measures from MD Anderson, a top-ranked cancer center.
In grade 1 tumors, the cells look close to normal. The higher the number, the more abnormal the cells look. Grade 4 tumors look most abnormal. To learn more about the system that describes tumor grade for your cancer, see the PDQ® cancer treatment summaries for adult and childhood cancers.
Healthcare providers use stages of cancer to diagnose disease, make treatment plans and collaborate with other cancer specialists. They base cancer staging on different factors, like tumor size, location and whether cancer cells have spread to other areas of your body.
A low grade number (grade 1) usually means the cancer is slower-growing and less likely to spread. A high grade number (grade 3) means a faster-growing cancer that’s more likely to spread.
For example, if prostate cancer has more grade 4 and 5 cells than any other, the doctor would add 4 and 5 to reach a Gleason score of 9.
The grade of a cancer describes how abnormal the cancer cells are, compared to healthy cells. This can help your cancer doctor understand how quickly the cancer may grow, or how likely it is to spread. Information about the stage and grade helps doctors plan the treatment you might need.
Grade 1 cancers usually grow more slowly. Grade 2, moderate or intermediate grade – the cancer cells look more abnormal and are growing slightly faster . Grade 3, high grade or poorly differentiated – the cancer cells look very different from normal cells and may grow more quickly.
Grade 1. Well differentiated, low grade. Grade 2. Moderately differentiated, intermediate grade. Grade 3. Poorly differentiated, high grade. Grade 4. Undifferentiated, high grade. What does the stage of a cancer mean? Once cancer is diagnosed, you will need more exams and tests to find out how much cancer is in your body and where it is.
Credit: Veer. Stage refers to the extent of your cancer, such as how large the tumor is and if it has spread. Knowing the stage of your cancer helps your doctor. understand how serious your cancer is and your chances of survival. plan the best treatment for you. identify clinical trials that may be treatment options for you.
The grade is a description of how abnormal the cancer cells look when they are examined with a microscope. This information can be used by an oncologist to estimate how likely it is for the tumor to grow and spread. This article will review the grading of tumors and how it impacts treatment decision-making.