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Symptoms. Effects of long-term benzodiazepine use may include disinhibition, impaired concentration and memory, depression, [ 19][ 20] as well as sexual dysfunction. [ 6][ 21] The long-term effects of benzodiazepines may differ from the adverse effects seen after acute administration of benzodiazepines. [ 22]
Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...
Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3][ 5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2] Reintroduced 2002 with restricted indication and ...
Senna glycoside. Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [ 1][ 5] The medication is taken by mouth or via the rectum. [ 1][ 6] It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. [ 3]
Chlordiazepoxide. Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol, benzodiazepines, and other drugs. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life.
The use of weight-loss products happens "at high levels in adolescents, especially girls," and can have long-term health consequences, they conclude. The meta-analysis included 90 studies with ...
Loperamide. Loperamide, sold under the brand name Imodium, among others, [ 1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [ 5][ 4] It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease, short bowel syndrome [ 4] Crohn's disease and ulcerative colitis. [ 5]
Constipation is the most common chronic gastrointestinal disorder in adults. Depending on the definition employed, it occurs in 2% to 20% of the population. [18] [58] It is more common in women, the elderly and children. [58] Specifically constipation with no known cause affects females more often affected than males. [59]