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H&E stain. Acinar cell carcinoma of the pancreas, also acinar cell carcinoma, is a rare malignant exocrine tumour of the pancreas. It represents 5% of all exocrine tumours of the pancreas, making it the second most common type of pancreatic cancer. [ 1] It is abbreviated ACC. It typically has a guarded prognosis.
Pancreatic cancer is among the most deadly forms of cancer globally, with one of the lowest survival rates. In 2015, pancreatic cancers of all types resulted in 411,600 deaths globally. [8] Pancreatic cancer is the fifth-most-common cause of death from cancer in the United Kingdom, [19] and the third most-common in the United States. [20]
A pancreatic tumor is an abnormal growth in the pancreas. [1] In adults, almost 90% are pancreatic cancer and a few are benign. [1] Pancreatic tumors are rare in children. [1] Classification is based on cellular differentiation (ductal, acinar, neuroendocrine, other) and gross appearance (intraductal, cystic, solid). [1]
surgical resection. Intraductal papillary mucinous neoplasm ( IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN tumors produce mucus, [ 1] and this mucus can form pancreatic cysts. [ 2] Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. [ 1]
Pancreatic neuroendocrine tumours ( PanNETs, PETs, or PNETs ), often referred to as "islet cell tumours", [ 1][ 2] or "pancreatic endocrine tumours" [ 3][ 4] are neuroendocrine neoplasms that arise from cells of the endocrine ( hormonal) and nervous system within the pancreas . PanNETs are a type of neuroendocrine tumor, representing about one ...
The Pancreatic Cancer Action Network ( PanCAN) is a United States-based 501 (c) (3) charity that funds research, provides patient/caregiver support, conducts community outreach and advocates for increased federal research funding for those affected by pancreatic cancer. [ 4][ 5] Since the disease is projected to become the second leading cause ...
The pancreatic duct is generally regarded as abnormally enlarged if being over 3 mm in the head and 2 mm in the body or tail on CT scan. [9] Pancreatic duct or parts of pancreatic duct can be demonstrated on ultrasound in 75 to 85% of people. [10] Pancreatic ductal carcinoma is a common form of pancreatic cancer.
Pancreatic stellate cells ( PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. [1] PaSCs are mediated by paracrine and autocrine stimuli and share similarities with the hepatic stellate cell. [1] Pancreatic stellate cell activation and expression of matrix molecules constitute the complex ...