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Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3][ 5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2] Reintroduced 2002 with restricted indication and ...
Originally available only by prescription, it was approved by the FDA for over-the-counter sale in February 2007. [32] In May 2010, the U.S. Food and Drug Administration (FDA) approved a revised label for Xenical to include new safety information about rare cases of severe liver injury that have been reported with the use of this medication. [33]
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...
In about half of people who are hospitalized or seen at a primary care clinic there is no documented reason for their long-term use of PPIs. [27] Some researchers believe that, given the little evidence of long-term effectiveness, the cost of the medication and the potential for harm means that clinicians should consider stopping PPIs in many ...
The list price of Ozempic is $892 per injector pen, which usually contains a month’s worth of medication. Ozempic is more likely to be covered by insurance if a patient has Type 2 diabetes. One ...
(Reuters) -The U.S. Food and Drug Administration on Wednesday approved Gilead Sciences' liver disease treatment, Livdelzi, which it gained through a $4.3 billion buyout of CymaBay Therapeutics ...
Senna glycoside. Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [ 1][ 5] The medication is taken by mouth or via the rectum. [ 1][ 6] It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. [ 3]