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Melanocytes are melanin -producing neural crest -derived [ 3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea ), [ 4] the inner ear, [ 5] vaginal epithelium, [ 6] meninges, [ 7] bones, [ 8] and heart found in many mammals and birds. [ 9] Melanin is a dark pigment primarily ...
Deaths. 59,800 (2015) [ 6 ] Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [ 1 ] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye ( uveal melanoma ). [ 1 ][ 2 ] In women, melanomas most commonly occur on the legs; while in men, on the ...
Pennsylvania. Pennsylvania ( / ˌpɛnsɪlˈveɪniə / ⓘ PEN-sil-VAY-nee-ə, lit. 'Penn's forest country' ), officially the Commonwealth of Pennsylvania[ b] ( Pennsylvania Dutch: Pennsylvanie ), [ 7] is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States.
August 13, 2024 at 2:33 PM. Michele Eve Sandberg/SIPAPRE/AP. Big Lots is closing more than 300 locations across the United States, or roughly a quarter of its stores, following an earlier warning ...
Psoriasis. Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [ 4][ 5] These areas are red, pink, or purple, dry, itchy, and scaly. [ 8][ 3] Psoriasis varies in severity from small localized patches to complete body coverage. [ 3] Injury to the skin can trigger psoriatic skin changes at that ...
Shingles. Shingles, also known as herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. [ 2][ 6] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [ 1] Two to four days before the rash occurs there may be tingling or local pain in the area ...
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