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This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. PAX8 releases the hormones important for regulating growth, brain development, and metabolism. Also functions in very early stages of kidney organogenesis, the Müllerian system, and the thymus. [ 7]
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PAX8 has been associated with thyroid specific expression. It transcribes a protein of 451 amino acids from 11 exons and 2,526bps in humans. Pax8 loss-of-function mutant mice lack follicular cells of the thyroid gland. [17] PAX9 has found to be associated with a number of organ and other skeletal developments, particularly teeth. It transcribes ...
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Since the office was established in 1789, 45 men have served in 46 presidencies. The first president, George Washington, won a unanimous vote of the Electoral College. [ 4] Grover Cleveland served two non-consecutive terms and is therefore counted as the 22nd and 24th president of the United States, giving rise to the discrepancy between the ...