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Renal physiology. This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology ( Latin rēnēs, "kidneys") is the study of the physiology ...
Kidney. In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [ 1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [ 2][ 3] They are located on the left and right in the retroperitoneal space, and in adult humans are about 12 centimetres ( 41⁄2 inches) in ...
Blood tests are also used to assess kidney function. These include tests that are intended to directly measure the function of the kidneys, as well as tests that assess the function of the kidneys by looking for evidence of problems associated with abnormal function. One of the measures of kidney function is the glomerular filtration rate (GFR).
The nephron is the minute or microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule extends from the capsule.
Anatomical terminology. [ edit on Wikidata] The renal circulation supplies the blood to the kidneys via the renal arteries, left and right, which branch directly from the abdominal aorta. Despite their relatively small size, the kidneys receive approximately 20% of the cardiac output. [ 1]
The juxtaglomerular apparatus (also known as the juxtaglomerular complex) is a structure in the kidney that regulates the function of each nephron, the functional units of the kidney. The juxtaglomerular apparatus is named because it is next to (juxta- [ 1]) the glomerulus . The juxtaglomerular apparatus consists of three types of cells:
The glomerulus ( pl.: glomeruli) is a network of small blood vessels ( capillaries) known as a tuft, located at the beginning of a nephron in the kidney. Each of the two kidneys contains about one million nephrons. The tuft is structurally supported by the mesangium (the space between the blood vessels), composed of intraglomerular mesangial cells.
Mesangial cells are specialised cells in the kidney that make up the mesangium of the glomerulus. Together with the mesangial matrix, they form the vascular pole of the renal corpuscle. [ 1] The mesangial cell population accounts for approximately 30-40% of the total cells in the glomerulus. [ 2] Mesangial cells can be categorized as either ...