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Alcohol detoxification (also known as detox) is the abrupt cessation of alcohol intake in individuals that have alcohol use disorder. This process is often coupled with substitution of drugs that have effects similar to the effects of alcohol in order to lessen the symptoms of alcohol withdrawal .
Alcohol withdrawal syndrome ( AWS) is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use. [1] Symptoms typically include anxiety, shakiness, sweating, vomiting, fast heart rate, and a mild fever. [1] More severe symptoms may include seizures, and delirium tremens (DTs); which can be fatal in ...
Banana bag. A banana bag (or rally pack) is a bag of IV fluids containing vitamins and minerals. The bags typically contain thiamine, folic acid, and magnesium sulfate, and are usually used to correct nutritional deficiencies or chemical imbalances in the human body. The solution has a yellow color, hence the term "banana bag".
Aaron White, a neuroscientist and senior scientific adviser to the director at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), agrees. “It only takes a drink or two for alcohol ...
Delirium tremens ( DTs; lit. 'mental disturbance with shaking') is a rapid onset of confusion usually caused by withdrawal from alcohol. [2] When it occurs, it is often three days into the withdrawal symptoms and lasts for two to three days. [2] Physical effects may include shaking, shivering, irregular heart rate, and sweating. [1]
Chlordiazepoxide. Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol, benzodiazepines, and other drugs. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life.
Alcohol is the leading cause of direct deaths from drug overdoses. Symptoms of ethanol overdose may include nausea, vomiting, CNS depression, coma, acute respiratory failure, or death. Levels of even less than 0.1% can cause intoxication, with unconsciousness often occurring at 0.3–0.4%. [275]
Clomethiazole is a potent CYP2E1 enzyme inhibitor which slows down the metabolism of ethanol, hence its use in alcohol withdrawal. It is also an inhibitor of CYP2B6 and possibly CYP2A6 and thus can affect the plasma clearance of substrates of those enzymes. When clomethiazole is administered via IV in addition to carbamazepine, its clearance is ...
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