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Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [6] [7] Specifically it is used for hormone receptor-positive breast cancer. [7] It has also been used to prevent breast cancer in those at high risk. [7] It is taken by mouth. [7]
A drug previously used to treat breast cancer is now being offered to high risk women as a preventative measure.. Scientists have found that the hormone therapy - called anastrozole - can p revent ...
Aromatase inhibitors ( AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.
AIs are divided into two categories, steroidal aromatase inhibitors (SAIs, type 1 inhibitors) and non-steroidal aromatase inhibitors (type 2 inhibitors) that is based on their mechanism of action and structure. NSAIs are mainly used to treat breast cancer in women. NSAIs binding is a reversible process where NSAIs binds to the aromatase enzyme ...
Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also ...
Tamoxifen, a nonsteroidal triphenylethylene antiestrogen and a widely used drug in the treatment of breast cancer. Selective estrogen receptor modulators ( SERMs ), also known as estrogen receptor agonist/antagonists ( ERAAs ), [ 1][ 2] are a class of drugs that act on estrogen receptors (ER). [ 3] A characteristic that distinguishes these ...
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