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Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease ...
The history of smallpox extends into pre-history. [1] Genetic evidence suggests that the smallpox virus emerged 3,000 to 4,000 years ago. [2] Prior to that, similar ancestral viruses circulated, but possibly only in other mammals, and possibly with different symptoms. Only a few written reports dating from about 500 AD to 1000 AD are considered ...
1775–1782 North American smallpox epidemic. George Washington by Charles Willson Peale, 1776. The New World of the Western Hemisphere was devastated by the 1775–1782 North American smallpox epidemic. Estimates based on remnant settlements say at least 130,000 people were estimated to have died in the epidemic that started in 1775.
The 1947 New York City smallpox outbreak occurred in March 1947 and was declared ended on April 24, 1947. The outbreak marked the largest mass vaccination effort ever conducted for smallpox in America. Within three weeks of the discovery of the outbreak, the U.S. Public Health Service, in conjunction with New York City health officials, had ...
Edward Jenner FRS FRCPE [1] (17 May 1749 – 26 January 1823) was an English physician and scientist who pioneered the concept of vaccines and created the smallpox vaccine, the world's first vaccine. [2] [3] The terms vaccine and vaccination are derived from Variolae vaccinae ('pustules of the cow'), the term devised by Jenner to denote cowpox.
1770s Pacific Northwest smallpox epidemic. The first known smallpox epidemic to strike the native peoples of the coastal and interior Pacific Northwest arrived in the early 1770s, devastating large swathes of the population and causing significant demographic collapse – both from the disease itself and corresponding malnutrition from the ...
The 1837 Great Plains smallpox epidemic spanned 1836 through 1840 but reached its height after the spring of 1837, when an American Fur Company steamboat, the SS St. Peter, carried infected people and supplies up the Missouri River in the Midwestern United States. [1] The disease spread rapidly to indigenous populations with no natural immunity ...
The index case was later discovered to be a nine-year old girl who arrived in the UK on 16 December 1961 from Karachi, Pakistan, where there was an ongoing epidemic of smallpox. The outbreak resulted in 14 cases of smallpox and contact tracing of over 1,400 individuals. Within five days either 250,000 or 285,000 people had been vaccinated.