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The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
In some countries, such as Brazil (photo) and France, more than 20% of all drug sales in units are generic. A generic drug (or simply generic) is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs ...
Bupropion was originally called by the generic name amfebutamone, before being renamed in 2000. [ 16 ] In 2022, it was the 21st most commonly prescribed medication in the United States, with more than 25 million prescriptions. [ 38 ][ 39 ] It is on the World Health Organization's List of Essential Medicines.
The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989 by a group led by pharmacologist David Bailey. Their first published clinical report on grapefruit drug interactions was in 1991. [9] The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit ...
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