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In Wikidata. Calcium channel blockers ( CCB ), calcium channel antagonists or calcium antagonists[ 2] are a group of medications that disrupt the movement of calcium ( Ca2+. ) through calcium channels. [ 3] Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension.
Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD) [ 10] and variant angina (also called Prinzmetal angina or coronary artery vasospasm, among other names). [ 11] It is taken orally (swallowed by mouth).
Urology. Overflow incontinence is a concept of urinary incontinence, characterized by the involuntary release of urine from an overfull urinary bladder, often in the absence of any urge to urinate. This condition occurs in people who have a blockage of the bladder outlet ( benign prostatic hyperplasia, prostate cancer, or narrowing of the ...
Nifedipine. Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. [ 2] It is one of the treatments of choice for Prinzmetal angina. [ 2] It may be used to treat severe high blood pressure in pregnancy. [ 2]
Compared with certain other L-type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil) that have significant action at the heart, the dihydropyridine calcium channel blockers lower blood pressure mainly by relaxing the smooth muscle of the blood vessel walls. [3]
Isradipine (tradenames DynaCirc, Prescal) is a calcium channel blocker of the dihydropyridine class. It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack . It was patented in 1978 and approved for medical use in 1989. [ 1]
Channel blocker. Tetrodotoxin, an example of a channel block molecule. A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell. Channel blocking is conducted by different types of molecules, such as cations, anions, amino ...
Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. [ 8] It may also be used in hyperthyroidism if beta blockers cannot be used. [ 8] It is taken by mouth or injection into a vein. [ 8]