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  2. DNA synthesis - Wikipedia

    en.wikipedia.org/wiki/DNA_synthesis

    DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules. DNA is a macromolecule made up of nucleotide units, which are linked by covalent bonds and hydrogen bonds, in a repeating structure. DNA synthesis occurs when these nucleotide units are joined to form DNA; this can occur artificially ( in vitro) or ...

  3. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    As DNA synthesis continues, the original DNA strands continue to unwind on each side of the bubble, forming a replication fork with two prongs. In bacteria, which have a single origin of replication on their circular chromosome, this process creates a "theta structure" (resembling the Greek letter theta: θ). In contrast, eukaryotes have longer ...

  4. Artificial gene synthesis - Wikipedia

    en.wikipedia.org/wiki/Artificial_gene_synthesis

    Artificial gene synthesis, or simply gene synthesis, refers to a group of methods that are used in synthetic biology to construct and assemble genes from nucleotides de novo. Unlike DNA synthesis in living cells, artificial gene synthesis does not require template DNA, allowing virtually any DNA sequence to be synthesized in the laboratory.

  5. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    Outline; Index; History and topics. ... DNA) is a polymer ... the polymerase recognizes the occasional mistakes in the synthesis reaction by the lack of base pairing ...

  6. Meselson–Stahl experiment - Wikipedia

    en.wikipedia.org/wiki/Meselson–Stahl_experiment

    Meselson–Stahl experiment. The Meselson–Stahl experiment is an experiment by Matthew Meselson and Franklin Stahl in 1958 which supported Watson and Crick 's hypothesis that DNA replication was semiconservative. In semiconservative replication, when the double-stranded DNA helix is replicated, each of the two new double-stranded DNA helices ...

  7. Oligonucleotide synthesis - Wikipedia

    en.wikipedia.org/wiki/Oligonucleotide_synthesis

    Oligonucleotide synthesis. Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure ( sequence ). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence.

  8. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome . DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ...

  9. Nucleic acid metabolism - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_metabolism

    Nucleic acid metabolism is a collective term that refers to the variety of chemical reactions by which nucleic acids ( DNA and/or RNA) are either synthesized or degraded. Nucleic acids are polymers (so-called "biopolymers") made up of a variety of monomers called nucleotides. Nucleotide synthesis is an anabolic mechanism generally involving the ...

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