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Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [ 1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [ 2][ 3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
Stem cell tourism is the part of the medical tourism industry in which patients travel to obtain stem cell procedures. [110] The United States has had an explosion of "stem cell clinics". [111] Stem cell procedures are highly profitable for clinics. The advertising sounds authoritative but the efficacy and safety of the procedures is unproven.
Peripheral stem cell transplantation. Peripheral blood stem cell transplantation ( PBSCT ), also called "Peripheral stem cell support", [ 1] is a method of replacing blood-forming stem cells. Stem cells can be destroyed through cancer treatments such as chemotherapy or radiation, as well as any blood-related diseases, such as leukemia, lymphoma ...
Stem cell secretome. The stem cell secretome (also referred to as the stromal cell secretome) is a collective term for the paracrine soluble factors produced by stem cells and utilized for their inter-cell communication. In addition to inter-cell communication, the paracrine factors are also responsible for tissue development, homeostasis and ...
A stem cell possesses two properties: . Self-renewal is the ability to go through numerous cycles of cell division while still maintaining its undifferentiated state. Stem cells can replicate several times and can result in the formation of two stem cells, one stem cell more differentiated than the other, or two differentiated cells.
Mesenchymal stem cells are able to alleviate heart fiber injury and prevent cardiac muscle cell death in mouse models of myocardial infarction, or heart attack, and prevent its further development. [20] [21] [22] They can migrate to areas of inflammation and decrease infarction and improve cardiac function.
A stem cell line is a group of stem cells that is cultured in vitro and can be propagated indefinitely. Stem cell lines are derived from either animal or human tissues and come from one of three sources: embryonic stem cells, adult stem cells, or induced pluripotent stem cells. They are commonly used in research and regenerative medicine.
Hematopoietic stem cell transplantation may be used to treat a number of conditions both congenital and acquired. Acquired. Malignancies. Hematological Leukemias. Acute lymphoblastic leukemia (ALL) Acute myeloid leukemia (AML) Chronic lymphocytic leukemia (CLL) Chronic myelogenous leukemia (CML), accelerated phase or blast crisis; Lymphomas ...